HPLC Column, Hyper Similars C8 Octyl, 5um, 4.0mm ID x 250mm Length, 150A. Cogent Brand. 1 EA. Special Order Item.
Additional Information:
Hyper Similars C8™ Octyl is a traditional reversed-phase HPLC stationary phase manufactured on high-purity Type-B spherical silica with a fully endcapped octyl (C8) bonded phase. Designed as a cost-effective alternative to legacy Hypersil® and Spherisorb® columns, it offers comparable chromatographic behavior for USP L7 methods while providing the moderate hydrophobic retention and reproducibility expected from a conventional C8 stationary phase. Compared to C18 columns, C8 phases generally provide reduced retention and faster elution of hydrophobic analytes.
62508-25P-4 is a 250 mm x 4.0 mm ID analytical column packed with 5 µm, 150Å Hyper Similars C8 particles. The extended 250 mm length provides increased theoretical plate counts and enhanced resolving power for impurity profiling, complex sample matrices, and difficult separations. The 5 µm particle size offers reliable performance with moderate operating pressure and broad compatibility with conventional HPLC systems. The 4.0 mm ID format is commonly used when reproducing legacy methods and typically operates at approximately 0.8–1.5 mL/min.
This USP L7 column is ideal for hydrophobic and neutral compounds when less retention is desired than a comparable C18 phase. Common applications include pharmaceutical analysis, long-chain fatty acid separations, impurity testing, and method development. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.
Key Benefits
Type-B spherical silica stationary phase
Suitable alternative for USP L7 methods
Comparable selectivity to Hypersil® and Spherisorb® C8 columns
Increased resolution from 250 mm column length
Reliable performance with 5 µm particles
Lower retention than C18 columns
Excellent for hydrophobic and neutral compounds
End-capped C8 bonded phase
Typical Applications
USP L7 methods
Reversed-phase HPLC
Pharmaceutical analysis
Impurity profiling
Method development
Long-chain fatty acid analysis
Quality control testing
Method transfer and validation
Specifications
Product Type: HPLC Column
Stationary Phase: Hyper Similars C8 Octyl
USP Classification: L7
Particle Size: 5 µm
Particle Type: Type-B Spherical Silica
Bonded Phase: C8 (Octyl)
Endcapped: Yes
Pore Size: 150Å
Column Dimensions: 4.0 mm ID x 250 mm
Length: 250 mm
Recommended Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Special Order Item Information
This item is a Special Order Item manufactured specifically to customer requirements.
Special Order Items cannot be canceled or returned once an order has been placed.
Manufactured upon receipt of order.
May have extended lead times compared to stocked products.
Important Notes
Designed for reversed-phase chromatography
Longer column length provides increased resolving power
Reliable operation on conventional HPLC systems
Lower operating pressure than smaller particle columns
Provides less retention than comparable C18 stationary phases
Excellent alternative for many USP L7 methods
Special Order Item